Abstract

Solitary plasmacytoma of bone (SPB) was defined as solitary osteolytic bone lesion with plasma cells collection, and lack of evidence of systemic myeloma. SPB has a higher risk of multiple myeloma (MM) progression and lower survival rate compared to extramedullary plasmacytoma, which is another form of plasmacytoma with soft tissue infiltration. Most of the SPB were discovered at axial skeletons and diaphysis of long bones which red marrow is predominant. Thoracic and lumbar vertebrae are the most frequent disease distribution, while clavicle involvements were rarely seen. We reported a case of solitary plasmacytoma of proximal clavicle, an extremely rare presentation, sustained a pathologic fracture under a low-energy trauma mechanism treated with tumor excision, plate fixation, and adjuvant radiotherapy, and showed excellent stability and functional outcome in 1 year follow-up.

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