Abstract
The paper presents the data available in the literature on the efficacy and tolerability of basic tumor necrosis factor α inhibitors (TNF α) etanercept, adalimumab, infliximab in the treatment of psoriatic arthritis (PsA) and their effects on the major manifestations of this disease - cutaneous and articular syndromes. It generalizes the authors experience in treating PA with infliximab. The value of TNF α inhibitors in the complex therapy of PsA and indications for their use in this disease are analyzed
Highlights
The paper presents the data available in the literature on the efficacy and tolerability of basic tumor necrosis factor α inhibitors (TNF α) etanercept, adalimumab, infliximab in the treatment of psoriatic arthritis (PsA) and their effects on the major manifestations of this disease — cutaneous and articular syndromes.
К 12 нед критериям АCR 20 соответствовали 59% больных основной группы и 15% контрольной (р
Через 2 нед после начала терапии критериям ACR 20 соответствовали 27% больных, а через 4 нед — 54%, в то время как в контрольной группе этот показатель составил всего 6 и 9%.
Summary
The paper presents the data available in the literature on the efficacy and tolerability of basic tumor necrosis factor α inhibitors (TNF α) etanercept, adalimumab, infliximab in the treatment of psoriatic arthritis (PsA) and their effects on the major manifestations of this disease — cutaneous and articular syndromes. К 12 нед критериям АCR 20 соответствовали 59% больных основной группы и 15% контрольной (р
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