Abstract
Type 17 T helper cells (Th17) are novel subsets of CD4+ effector T cells discovered recently which are different from the traditional type 1 and type 2.They are mainly differentiated from initial T cell precursor.Tumor microenvironmental cytokines can recruit CD4 + Th17 cells from the peripheral blood into tumor sites.And the differentiation of Th17 cells is also affected by tumor microenvironmental factors.Tumorinfiltrating Th17 cells play a dual role for tumor growth in both pro- and anti-tumourigenic processes.A further understanding of the activities of Th17 cells will provide a new breakthrough point for the researches of cancer immunotherapy. Key words: Neoplasms ; Inflammation; Th17 cell
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