Abstract

IntroductionMost patients referred for lung biopsy have a focal lesion that is likely to be a carcinoma and fine needle aspiration (FNA) is usually sufficient to confirm diagnosis. Percutaneous cutting needle biopsy (CNB) is an important and potential diagnostic technique when non carcinomatous disease is suspected or when the pulmonary disease is unclear, so tissue architecture is very important.Case presentationWe present a case of a 24 year old male arrived at our hospital with dyspnea and unusual computed tomography (CT) findings of sarcoidosis. Chest X-ray and CT scan revealed multiple masses in both lungs suggesting lung metastasis. Bronchoscopy and bronchoalveolar lavage did not reveal any malignant cells. None of the laboratory examinations revealed any primary extrapulmonary tumor. The patient underwent CT-guided core needle biopsy. Histopathological examination confirmed the diagnosis of sarcoidosis.ConclusionCT-guided core needle biopsy is a very helpful diagnostic tool in order to determine the benign or malignant nature of a thoracic lesion.

Highlights

  • Most patients referred for lung biopsy have a focal lesion that is likely to be a carcinoma and fine needle aspiration (FNA) is usually sufficient to confirm diagnosis

  • cutting needle biopsy (CNB) on the other side, provides cores of tissue for histological evaluation, the American Thoracic Society Guidelines have stated that CNB should not be used in the diagnosis of diffuse lung disease (DLD) [6]

  • The patient was placed in the appropriate position considering the location of the lesion. It is an increasing safe procedure in the Using a spiral computed tomography (CT), 5 mm slices were taken in order to determination of malignant and non-malignant lesions. specify the exact skin entry point, for the needle insertion

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Summary

Introduction

FNA of focal pulmonary opacities is an accepted technique for the diagnosis of carcinoma, with a reported sensitivity greater than 90% [1,2]. Complication rates are of 29-45% [3] It is much less successful in the diagnosis of benign focal lesions, diffuse lung disease (DLD), or when the pulmonary disease is unclear, in which case tissue architecture is important [2,3,4,5]. The patient was placed in the appropriate position considering the location of the lesion It is an increasing safe procedure in the Using a spiral CT, 5 mm slices were taken in order to determination of malignant and non-malignant lesions. Case presentation A 24-year old male (of greek origin and nationality) presented to our hospital complaining dyspnea He underwent a chest X-ray that revealed multiple bilateral pulmonary masses. It revealed multiple epitelioid cell granulomas with giant cells, in the absence of microbiological or virological abnormalities

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15. Moller DR
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