Abstract
The incorporation of thymidine-H 3 into DNA has been studied in high-speed supernatants of extracts of lung, kidney, liver, and spleen of normal rats and of rats bearing the Walker 256 carcinoma and the Jensen sarcoma. An increased incorporation was observed in the supernatants of the liver and the spleen of the tumor-bearing hosts as compared with that of the normal controls. The effect of the Jensen tumor on the incorporation was shown to be more pronounced than that of the Walker carcinoma. This increased activity was also found when the incorporation of thymidine-H 3 was studied in the supernatant fractions of the tumors themselves.
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