Étude comparative sur les antécédents d’interruption volontaire de grossesse dans une population de femmes infertiles et dans une population de femmes accouchées

Abstract

Objective For years, induced abortions (IA) have been deemed responsible for altered fertility. The implication of various mechanisms including tubal infertility, intra-uterine adhesions, spontaneous abortion, ectopic pregnancy, cervical incompetence, shortened gestations, and any psychological trouble leading to anovulation has been raised. Though many authors find no evidence of an increased risk on fertility for women, whose IA is not complicated by infection, it might sometimes be insinuated that infertility is the consequence of previous abortion. Thus, we compared the rate of patients with any prior IA in a population of newly delivered women and in women ongoing IVF. Patients and methods A retrospective study was conducted at Sèvres hospital, comparing two populations of women, newly delivered women ( n = 1738) between January 1st and December 31st 2005, and women ongoing IVF at the same period ( n = 430). We reported the number of previous medical or surgical induced abortions and compared it in both groups. Another analysis compared these rates, among two subgroups of women with one or more prior pregnancy (secondary infertility ( n = 148), and secondary gestation ( n = 1088). Results The rate of prior IA was not different in the two populations. In the IVF group, 13% ( n = 56) had undergone one or more IA, versus 16.7% ( n = 291) in the newly delivered group ( P = 0.06). Among women with previous pregnancy, 37.8% (56) women of the IVF group had undergone one or more previous IA, versus 26.7% (291) of the newly delivered women ( P = 0.007). Discussion and conclusion As expected by literature data on IA and fertility, rates of prior induced abortions were not different in the population of fertile women versus infertile. However, women with one or more previous pregnancy are more likely to have undergone previous IA in the IVF group than in the newly delivered group, possibly due to a bias of age. More data are requested to eliminate linkage between IA and infertility.