Tubérculo coroideo asintomático en un paciente con enfermedad de Crohn en tratamiento con adalimumab

Abstract

IntroductionAdalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. Case reportThe case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy. DiscussionChoroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab.