Abstract
Nutritional support was the mainstay of tuberculosis (TB) treatment before the advent of anti-TB drugs. Owing to the difficulty of curing patients with antimicrobial drug resistance, there is renewed interest in nutritional support in the management of TB. TB causes anorexia, weight loss, and cachexia. The goal of nutritional interventions is to compensate for the effects of TB on metabolism and to support the increased activity of the immune system. A careful assessment of nutritional status should be performed before assigning a supplementation regimen. Supplementation of multiple micronutrients during treatment has been associated with reduced mortality regardless of HIV status. Owing to its interference with vitamin B6 metabolism, isoniazid should be administered with vitamin B6 supplements.
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