Abstract

The objective was to analyze the trend in tuberculosis mortality in Paraná from 1998 to 2012, according to healthcare macro-region-al, gender and age. Ecological study of time series data with the system of the Unified System Mortality Information Health (SIM/SUS). Trend analysis of standardized mortality rates was performed by linear regression segmented identifying the points with the change trend. There were 847 deaths of residents in Paraná in the period. The trend was initially declining to state, with subsequent significant increase only for the macro-regional East. Mortality from tuberculosis showed growing trend for the age groups 20-39 years and 40-49 years and for males. The growing trend in tuberculosis mortality was observed from 2010 is a warning to managers honing the service at different levels of health care.

Highlights

  • Tuberculosis remains as the most important cause of morbidity and mortality among infectious diseases worldwide

  • Regarding the tuberculosis mortality trend by sex, despite the fluctuations and an evident growth for males from 2010, the joinpoint regression analysis showed no significant trend for either sex

  • The significant overall trend found for the state of Paraná was decreasing from 2005 to 2010 and stable after this period, and is partly consistent with the findings of a study conducted in São Paulo, SP10, which observed an increase in the number of deaths from tuberculosis as of 2005, but found later decrease and an increase forecast as of 2011

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Summary

Introduction

Tuberculosis remains as the most important cause of morbidity and mortality among infectious diseases worldwide. It accounts for a quarter of preventable deaths in developing countries, with emphasis on adults generally and men aged 45-59 years old[1,2]. It is known as the “neglected calamity” not yet resolved in this century[3]. Despite prevention and control measures adopted by health services across the country, the mortality rate of tuberculosis is still high. Deaths from tuberculosis may be related to factors such as HIV/Tb co-infection, advanced age, the male sex, drug resistance, history of noncompliance with treatment, alcoholism, as well as delay to diagnose the disease and start the treatment[4]

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