Tu1932 Ccl1 Antisense ODN Gene Therapy for Monocytes Is Prevented for the Progression of Hepatocellular Carcinoma in Humanized Chimeric Mice

Abstract

G A A b st ra ct s death or censored at time of last contact (median follow-up 251 days (d), range 0-1758 d). Survival rates were analysed using the Kaplan-Meier method. Pearson's correlation analyses were performed with respect to survival times and concentrations of IGF-1 and DKK-1. Results. At the time of the analysis 54 patients had died. The concentrations of IGF-1 significantly correlated with survival (0.324, p < 0.01) while the concentration of DKK-1 did not (-0.109, p = 0.197). Survival times using previously published cut-offs for BALAD2 score [-0.91] and IGF-1 [30 ng/ml] are given in table 1. Conclusion. IGF-1 and the BALAD-2 score are valuable to predict survival in patients with hepatocellular carcinoma.