Abstract
Large hyperplastic foregut polyps typically arise from chronically inflamed mucosa, present with bleeding or pain from prolapse, and have a <2% malignant potential. When malignancy is present, neoplasia is usually focal and lymph node involvement and metastases are rare. Due to the highly vascular nature of these polyps and low risk for malignancy, removal for histology is both dangerous and unnecessary in most cases, especially in those with comorbidities. Challenges include inability to fully encircle lesions to secure the stalks even with large snares, presence of thick stalks that cannot be clipped, and difficult positioning.
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