Tu1616 The Efficacy of Salvage Endoscopic Submucosal Dissection in Patients With Recurrent or Residual Tumor After Chemoradiotherapy for Esophageal Squamous Cell Carcinoma

Abstract

Local recurrent or residual tumor after chemoradiotherapy (CRT) for esophageal squamous cell carcinoma remains an important problem. Although salvage esophagectomy after CRT is the only curative possibility, it carries a higher mortality and morbidity rate than primary surgery. If the carcinoma is a superficial lesion that is limited to the superficial submucosal layer, endoscopic mucosal resection (EMR) may be effective as salvage treatment. However, salvage EMR has problems: lifting is not easy because of submucosal fibrosis; it has a low complete en bloc resection rate; and a positive vertical margin can occur in submucosal invasive cancer.