Abstract

Esophageal squamous cell papilloma (ESP) is a rare entity, with little data on etiology and long-term follow-up in the published literature. While the human papilloma virus (HPV) may play a causative role worldwide, the only study in the United States of 23 cases of ESP found that only 4% expressed HPV. Thus, there remains controversy regarding its role in the pathogenesis of these lesions. The aim of this study was to evaluate the incidence of HPV in of ESP in a large U. S. tertiary care center and to determine the long-term follow-up of patients who have had ESPs removed.

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