Tu1152 METHYLENE BLUE INFUSION COLONOSCOPY CAN IMPROVE THE DETECTION RATE OF LESIONS

Abstract

To analyze whether the Methylene blue infusion colonoscopy improves the detection rate of lesions compared with water-infusion. A total of 22 patients aged 18-80 years who underwent first colonoscopy at the Second Affiliated Hospital of Xi'an Jiaotong University were enrolled. The first colonoscopy was performed by water-infusion method. If polypoid lesion Ip/Is or non-polypoid lesions IIa/IIb/IIc were found, the location, size, shape were recorded, and they were admitted into hospital for further treatments. During the second colonoscopy, methylene blue solution was injected instead of water. If the lesion was found, the location, size, shape were recorded and the lesions would be resected by snare. Pathological examination was performed to confirm the nature of the lesion. Methylene blue solution was formulated as 40 mg methylene blue dissolved into 250 ml normal saline. At present, 22 patients were collected, including 6 females and 16 males, with an average age of 60.6 years. They had a total of 32 colorectal lesions and 8 adenomas detected by water-infusion colonoscopy. At the second procedure, a total of 138 colorectal lesions and 36 adenomas were found under the methylene blue infusion colonoscopy. The overall lesions detection rate increased by (66.13±9.48)%, the adenoma detection rate increased by (81.00±14.51)%. There was no significant difference in patient experience, operation time and complications. Methylene blue infusion colonoscopy can significantly improve the detection rate of lesions compared with water-infusion colonoscopy.