Abstract

The sex-chromatin test and the chromosome analysis are reviewed briefly in relation to the sexual development in normal and known abnormal conditions. Two cases of true hermaphroditism are reported. Chromosome analysis showed normal feminine constitution in both. Microscopical investigation of the ovotestis removed from case I showed the ovarian stroma without follicles with changes completely as in Turner's syndrome. The testicular elements had features in common with Klinefelter's syndrome. The tubules were completely hyalinized containing Sertoli cells only. Spermatogenic elements were not observed. The Leydig cells were numerous and often found in small adenomas. Case II was reported by Zachariae in 1955.

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