“True” Chirality Transfer from Silicon to Carbon: Asymmetric Amplification in a Reagent‐Controlled Palladium‐Catalyzed Hydrosilylation

Abstract

Borne by silicon: A silicon reagent with Si-centered chirality induces C-centered chirality in CSi bond formation. All of the stereochemical information stems from the chiral silane. This first “true” chirality transfer from silicon to carbon has been realized in a Pd-catalyzed hydrosilylation of a prochiral alkene. Moreover, this reagent-controlled process displays an unusual positive nonlinear effect (see Scheme).