Troponin: the Valuable Assay in Post Mortem Investigation of Ischemic Heart Disease

Abstract

Sudden, unexplained and unexpected but natural deaths are more common in adults than it can be presumed with no age or sex exemption. It is found more common in younger one. History or circumstances are nonspecific to give cause of death. In such type of incidences meticulous postmortem examination is necessary with various laboratory investigations like histopathology, bacteriology, biochemistry, serology and toxicology. Amongst natural sudden deaths, coronary atherosclerosis and/or its effect(s) is the most common cause. In such cases of sudden death Meticulous & detailed Autopsy is necessary with all above cited laboratory investigations. In cardiac death, Troponin is the best biomarker to detect cardiac damage as there is increase in Troponin in blood after cardiac damage & Troponin levels if raised are highly specific for cardiac damage or injury. In our study, we aimed to find out the role of Troponin assays to establish the cardiac damage at the time of autopsy.