Abstract
OBJECTIVE: To determine the usefulness of comprehensive chromosome screeniong (CCS) by TE biopsy in gestational surrogacy DESIGN: Retrospective case control study MATERIALS AND METHODS: Data from all cycles involving nondonor egg embryo transfers to gestational carriers (GC) at our center from April 2008 to January 2015 were reviewed. FDA screening guidelines were adhered to in all cases. Embryos of the intended parents (IP) were created as per routine IVF protocol. There were a total of 88 embryo transfer cycles. Twenty eight cycles involved the transfer of frozen eupolid blastocysts after TE biopsy. Embryos were screened for all 24 chromosomes by array CGH (group A). Of the remaining 60 cycles (group B), there were 35 fresh, and 25 frozen transfers. One fresh transfer was canceled due to embryo arrest. Paired student t-test and the Chi-squared test of independence were used for statistical analysis. P value <0.05 was considered statistically significant. RESULTS:
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