Abstract
Two patients are reported with localized scleroderma who developed thrombocytopenia. One of these patients had a positive antinuclear antibody (ANA) and Anti-DNA antibodies tests. The occurrence of thrombocytopenia in localized scleroderma suggests an autoimmune mechanism, by the response to steroids and the presence of positive autoantibodies. This possible association emphasizes the need to look for hematologic disorders in patients with systemic, as well as localized scleroderma.
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