TÜRKİYE'DE KAN GRUBU ARAŞTIRMALARI

Abstract

in this study, the discovery of blood groups, the inheritance of the blood groups and the importance of the research concerning of the blood groups as well as purpose of the determination of the blood groups gene freguencies are briefly discussed. Early articles and researches carried on blood groups in Turkey are reviewed chronologically. Furthermore the geographical distribution of the research locations and the number of the samples are shown. The first work on the rational distribution of the blood groups in Turkey was carried out in 1918 and since then number of research workers hav e studied on this subject tul 1958. However the results of these studies cannot be regarded to be an overall picture of Turkey for two main reasons: a) An inadeauate number of representative samples, b) The lack of application I or misapplication of statistical methods in data analyses. During a health survey undertaken in Van, a provincial town in Eastern Anatolia, carried out by The Directorate of Health of City of Van, the blood groups were also determined from the volunteers, it is the results of this survey that forms our survey data. in this survey the phenotype ratios and gene freguencies of ABO blood groups and Rh factors sampled from 6982 individuals were determined. The result of the survey indicates that the distribution of blood groups are: %39.90 A, %17.09 B, %14.66 AB, and %28.26 O. it is also found that the gene freguency of A is 0.2945, B is 0.1738, O is 0.5315 respectively. Furthermore the distribution of positive Rh factor appears to be % 89.49 whereas negative factor is in the order of %10.51. In our work, the results of 8 previous work which are considered to be of representative of Turkey as a whole, together with 4 regional studies, which were carried out in Diyarbakir (2), Trakya (I) and Adana, Kayseri, Trabzon (3 provinces together) were investigated in comparison with the results of our study. It appears that A blood group and A gene frequency show a gradual decrease from west to east on B blood group and B gene frequency. It is also observed that O blood group and O gene frequency show a similar pattern to the A blood group. When regional distribution of the research results is considered, it is apparent that the majority of the results of Eastern Anatolian Region is consistent with the results of the Van survey. At present as a result of recent developments in transportation, industrialization, technology and technical progress and immigration resulted in the increased rate of mixing of different human groups. The distribution ratios of blood groups are one of the most indisputable evidence of human mixture.