Trizomi 13 ve 18 ile ilişkili prenatal sonografik bulgular; tek bir merkezde prenatal tanı konmuş olguların sunumu

Abstract

Purpose: In this retrospective study, we aimed to evaluate the prenatal sonographic findings of the fetuses with trisomy 13 and 18. Materials and Methods: The sonographic findings of fetuses which were prenatally diagnosed as trisomy 13 and 18 were retrospectively reviewed in two years’ period at a single tertiary perinatal center. The most common findings for each aneuploidy were described. Results: Total 13 cases were diagnosed as trisomy 13 or 18 during two years’ period of which three cases were trisomy 13 and 10 cases were trisomy 18. Major sonographic abnormality associated with trisomy 13 was holoprosencephaly while cardiac abnormalities were the leading finding for trisomy 18. Conclusion: Trisomy 13 and 18 have major prenatal sonographic findings that may be detected with a targeted sonographic examination. Fetal cardiac and central nervous system abnormalities are the primary major findings associated with trisomy 13 and 18.