Abstract
We report a simple synthesis of a variety of tritiated alkenes with high specific activity. In each case, the trisylhydrazone derivative of the ketone was converted to the vinyllithium intermediate, which was then quenched with high specific activity tritiated water to generate the corresponding tritiated alkene. The specificity of tritium labelling was determined by tritium NMR spectroscopy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have