Abstract
Natural sterols and triterpenoids are pharmacologically active compounds that possess antibacterial and hypocholesterinemic action and relieve cramps [1]. Furthermore, sterols (cholesterol, ergosterol, sitosterol) are used to prepare steroid hormones and vitamin D. Sterols play a structural role in plant-cell membranes [2]. Plants of the Pulicaria (Asteraceae) genus contain clerodane [3, 4], caryophyllene [5, 6], and guaiane [7, 8] terpenoids and flavonoids [9, 10] that have valuable biological properties. In continuation of a study of terpenoid compounds from the Pulicaria genus, we investigated hexane fractions of the CHCl extract of three species of fleabane: P. salviifolia, P. gnophaloides, and P. uliginosa. The raw material was the aerial 3 part of the plants that was collected during fruiting near Pungan in Namangansk district. Total P. salviifolia was chromatographed on a KSK silica-gel column with elution by benzine-ethylacetate followed by volume increase. Two compounds of triterpenoid and sterol nature were isolated. Compound 1, C H O , mp 221-222 C, [ ] +95.9 (c 1.0, CHCl ). IR spectrum: 1642, 1729, 2857-3073 cm . 32 52 2 o o D 3 -1
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