Abstract
BackgroundIdentification of chemical constituents is very important for ensuring the function of traditional herbal medicine. The objectives of this study were to determine the activity chemical constituents of Lysimachia candida Lindl. MethodsSolvent fractionation and chromatographic separation techniques were used to isolate the chemical constituents of Lysimachia candida Lindl. ResultsThree triterpenoid saponins were isolated from the antifungal activity fraction of Lysimachia candida Lindl. Their structures were elucidated on the basis of spectroscopic data. They were established as a new compound 3-O-[β-d-Xylopyranosyl-(1→2)-β-d-Glucopyranosyl-(1→4)-[β-d-Glucopyranosy-(1→2)]-α-l-arabinopyranoside]-13,28-Epoxy-3,16,22-oleananetriol, named Lysimanoside (1), along with two known compounds Lysikokianoside I (2) and Anagallisin C (3). ConclusionAnagallisin C showed to be the main antifungal compound against Aspergillus flavu. in Lysimchia candida Lindl.
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