Abstract

A novel sorbicillin trimer, trisorbicillinone A ( 1), was isolated from a deep sea fungus, Phialocephala sp. FL30r. The structure and relative stereochemistry of 1 were determined based on spectroscopic methods. Trisorbicillinone A ( 1) showed cytotoxicity against P388 and HL60 cells with the IC 50 value of 9.10 and 3.14 μM, respectively.

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