Abstract
Identification of cytogenetic abnormalities plays an important role in the diagnosis and prognosis of leukemias. We report three cases of trisomy 6 as sole cytogenetic abnormality in acute myeloid leukemia (AML). Short-term unstimulated bone marrow culture showed two cases of AML-M1 and one case of AML-M2 with trisomy 6. It is known that trisomy 6 is a rare numerical abnormality and prognostic significance is not well established. More studies are required to assign the role of trisomy 6 in the development of leukemia as well as in prognosis.
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