Triple antibiotics: A synergistic approach to combating infection

Abstract

The utilization of Triple Antibiotic Paste (TAP) in dentistry has emerged as a significant development in endodontic and odontogenic infection management. With increasing cases of odontogenic infections, particularly in the context of the complex root canal anatomy, the selection of appropriate medicaments and disinfectants has become imperative. (1) In situations where conventional manual preparation and irrigation prove inadequate, TAP stands out as an intracanal disinfectant comprising a combination of three antibiotics, exhibiting a synergistic antimicrobial effect against a wide spectrum of microorganisms. This review outlines the multifaceted applications of TAP in dentistry, from its composition and clinical utility to its potential in preserving the vitality of diseased pulp. It also acknowledges the limitations and drawbacks associated with TAP's application, emphasizing the need for precise administration. Furthermore, it discusses TAP's role in primary teeth, expanding its scope beyond conventional endodontics. This research investigation explores the latest insights and considerations surrounding the "triple antibiotic paste" (TAP) and its applications in the field of dentistry, with a particular focus on endodontics.