Abstract

Drug-induced hypoglycemia is an important consideration in the differential diagnosis of altered mental status, especially in the elderly patient. Symptoms can be insidious, causing subtle mental status changes. In addition to the well known hypoglycemic effects associated with treatment of diabetes mellitus, several commonly prescribed medications, such as thiazides, sulfonylureas, and. some antibiotics, can cause hypoglycemia. We describe a case of hypoglycemia in an elderly patient taking sulfonamide antibiotics. Previous reports in the medical literature have described this occurrence with sulfonamides, all in renally impaired patients or in those who were also taking sulfonylurea drugs. Although the incidence of drug-induced hypoglycemia is rare in the general population, its incidence is not uncommon in elderly and diabetic patients.

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