Abstract

Researchers in Canada previously demonstrated that patients who are taking both trimethoprim-sulfamethoxazole (TMP/SMX) and spironolactone are at excess risk for being hospitalized with hyperkalemia (NEJM JW Gen Med Nov 1 2011 and BMJ 2011; 343 : d5228). Now, the same team has performed a population-based case-control study in Ontario to determine whether this interaction might confer risk for sudden death, …

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