Trimetallic PEPPSI‐Type Palladium N‐Heterocyclic Carbene Complexes – Improved Catalyst Lifetime in the Mizoroki–Heck Coupling Reaction

Abstract

AbstractA series of mono‐ and dendritic trimetallic PEPPSI‐type (pyridine‐enhanced precatalyst preparation stabilization and initiation) complexes bearing N‐heterocyclic carbene (NHC) ligands containing a protected amine in the form of an ethylphthalimido group have been synthesized. These discrete prototypes of complexes covalently bound to suitable supports have been studied in the Mizoroki–Heck coupling of aryl iodides under mild conditions, including sets of experiments to assess the lifetime of the active species. The palladated dendrons are more efficient and robust catalysts than their monometallic counterparts.