Abstract
Serum cholesterol and triglyceride values were compared in two groups of patients with gouty arthritis, one in which the gout was associated with chronic lead nephropathy and another in which lead could be excluded and the gout be regarded as primary. Significant hypertriglyceridemia without hypercholesterolemia was found in the primary gout group. Comparison confirmed greater obesity and alcohol consumption in the primary group group, but their presence did not correlate well with the hypertriglyceridemia. Analysis showed that the greater hypertriglyceridemia in the primary goup group persisted even when allowance was made for their greater weight and alcohol consumption. No correlation was demonstrable between the degree of hypertriglyceridemia and the degree of overproduction of urate, as judged by the urinary excretion of uric acid. It is suggested that it is important to define the features of this type of gout associated with hypertriglyceridemia in order to elucidate its mechanism. Serum cholesterol and triglyceride values were compared in two groups of patients with gouty arthritis, one in which the gout was associated with chronic lead nephropathy and another in which lead could be excluded and the gout be regarded as primary. Significant hypertriglyceridemia without hypercholesterolemia was found in the primary gout group. Comparison confirmed greater obesity and alcohol consumption in the primary group group, but their presence did not correlate well with the hypertriglyceridemia. Analysis showed that the greater hypertriglyceridemia in the primary goup group persisted even when allowance was made for their greater weight and alcohol consumption. No correlation was demonstrable between the degree of hypertriglyceridemia and the degree of overproduction of urate, as judged by the urinary excretion of uric acid. It is suggested that it is important to define the features of this type of gout associated with hypertriglyceridemia in order to elucidate its mechanism.
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