Abstract

Water-soluble, acrylate-terminated poly(β-amino esters) with built-in trigger-responsive domains were synthesized through Michael addition of trigger-responsive diacrylates and primary amines. They were used as macromolecular precursors for photoinitiated cross-linking reactions to prepare trigger-responsive hydrogels for protein encapsulation. The encapsulated proteins could be rapidly released upon external triggering.

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