Trigger of oocyte maturation with low-dose human chorionic gonadotropin (hCG) reduces the risk of ovarian hyperstimulation syndrome (OHSS) and improves IVF outcome

Abstract

10,000 IU hCG has been routinely used for the induction of oocyte maturation in the IVF treatment, but there is no solid scientific evidence to support whether 10,000 IU hCG is really needed to induce oocyte maturation. In this study, we compared the risk of OHSS development, oocyte maturation rate and IVF success rate in the high-risk patients after 5,000 IU hCG vs 10,000 IU hCG triggers in donor or non-donor IVF cycles.