Abstract

AbstractNeuralgia can be defined as paroxysmal, intense intermittent pain that is usually confined to specific nerve branches to the head and neck. The trigeminal nerve is responsible for sensory innervation of the scalp, face and mouth, and damage or disease to this nerve may result in sensory loss, pain or both. >85% of cases of Trigeminal Neuralgia are of the classic type known as Classical Trigeminal Neuralgia (CTN), while the remaining cases can be separated to secondary Trigeminal Neuralgia (STN). STN is thought to be initiated by multiple sclerosis or a space-occupying lesion affecting the trigeminal nerve, whereas the leading cause of CTN is known to be compression of the trigeminal nerve in the region of the dorsal root entry zone by a blood vessel. There is no guaranteed cure for the condition of Trigeminal Neuralgia, but there are several treatment options that can give relief. In this chapter, we review the common neuralgias occurring within the oral and maxillofacial region with special emphasis on Trigeminal Neuralgia. We will discuss the historical evolution of treatment including the medical and surgical modalities with the use of current literature and newer developments. It has been highlighted that the first line of treatment for trigeminal neuralgia is still pharmacological treatment, with Carbamazepine and Oxcarbazepine being the first choice. Possible surgical methods of treatment are discussed within this chapter including modalities such as Microvascular Decompression, Gamma Knife Radiosurgery and Peripheral Neurectomy. As an OMF surgeon, it is important to obtain a good clinical history to rule out other pathology including dental focus. Many clinicians involved ranging from primary care dentists and doctors to secondary care (neurologists, Oral Medicine, OMFS, etc.) to deliver the appropriate first course of action, which is the medical management. The management of TN patients should be carried out in a multidisciplinary setting to allow the patients to choose the best-suited option for them. It is also important to set up self-help groups to enable them to share knowledge and information for themselves and their family members for the best possible outcomes.

Highlights

  • Neuralgia can be defined as paroxysmal, intense intermittent pain that is usually confined to specific nerve branches of the head and neck

  • This severe medical condition affects one or more branches of the fifth cranial nerve known as the trigeminal nerve, which is the largest cranial nerve and has both sensory and motor functions. >85% of cases of trigeminal neuralgia are of the classic type known as classical trigeminal neuralgia (CTN), while the remaining cases can be separated to secondary trigeminal neuralgia (STN)

  • Trigeminal Neuralgia (TN) is the most severe type of pain humans ever face for an innocuous touch without any force, and it is debilitating to an extent that it was described historically as “suicide disease” until the development of the medications and various surgical procedures in the 1950s

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Summary

26.1 Introduction

Neuralgia can be defined as paroxysmal, intense intermittent pain that is usually confined to specific nerve branches of the head and neck. Trigeminal Neuralgia (TN), referred to as ‘Tic Douloureux,’ is sought to be the most intense and wellknown neuralgias, which displays classical features of intense sharp, stabbing sensations with or without burning pain throughout the face It is considered as one of the most chronic painful conditions known within the body. The pain, which is often initiated by just a light touch to an area of skin, can occur at any time without warning and depending on the severity of the condition, the frequency of the attacks can vary This severe medical condition affects one or more branches of the fifth cranial nerve known as the trigeminal nerve, which is the largest cranial nerve and has both sensory and motor functions.

26.2 Anatomy of the Trigeminal Nerve
Posterior Division
26.3.3 Tumour and Cyst
26.3.4 Diabetes Mellitus
26.3.5 Herpes Simplex
26.4 Pathophysiology of TN
26.5 Historical Perspective
26.6 Clinical Presentation
26.6.1 Risk Factors
26.6.2 Prevalence
26.6.3 Clinical Diagnosis
26.6.4 Glossopharyngeal Neuralgia
26.7 Investigations
26.8.1 Medical Management
26.8.2 Surgical Management
26.9.1 Infraorbital Neurectomy
26.9.2 Inferior Alveolar Nerve or Mental Nerve Neurectomy
26.9.3 Cryotherapy
26.9.4 Alcohol Block
26.9.5 Other Peripheral Procedures
Findings
26.10 Conclusion
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