Trifluoroborane catalyzed chemoselective synthesis of highly functionalized 1,3‐thiazin‐2‐ylidenes

Abstract

AbstractAn efficient chemoselective synthesis of 1,3‐thiazine‐2‐ylidenes was achieved via annulations of β‐aroyl‐thioacetamide with propargyl alcohols using BF3 OEt2 as Lewis acid catalyst. A broad spectrum of substrates was well tolerated under the mild reaction conditions producing desired thiazine heterocyclics in good yields.