Abstract
Electrical impedography was employed in the study of the effects on rat brain of chronic intoxcation with triethyltin sulfate. Behavioral and pathologic changes were the same as those reported else-where in the literature. The impedance data is new and consists of a progressive increase in cerebral resistance during the period of time when trietyhltin sulfate is being administered. Since this represents essentially a measurement of the resistive properties of extracellular space, it is indicative of either a decrease in its volume, a decrease in its conducting elements, or both. It is suggested that it may be largely due to change in conductivity associated with hypotonicity.
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