Abstract
Introduction: In emergence a COVID patient with multisystem inflammatory syndrome in children (MIS-C), associated with SARS-CoV-2, has shown increasing number among pediatric. Even the same presentation of Kawasaki disease we have to keep in mind MIS-C, in order to reach a consensus on this new disease in the future. Three variations of the disease patterns were reported: a group of children with increase in inflammatory activity and persistent fever, without criteria for Kawasaki disease, a second group with Kawasaki disease criteria, and a third group with shock, coronary aneurysms, severe cardiac dysfunction, and gastrointestinal symptoms. Classic Kawasaki disease is self-limited vasculitis which affects medium-sized vessels, almost occurred in children under five years old. Here, we bring a Saudi case, present to emergency department in Prince Sultan Military Medical City. Case report: 10 years old female, medically free, presented with abdominal pain, fever and skin rashes. Patient had history of COVID-19 infection 1 month before presentation. Initial investigations showed acute kidney injury with elevated inflammatory markers. Conclusion: Further evidence of the increase in the incidence of pediatric MIS-C, temporarily is associated with SARS-CoV-2. Physician should give more attentions to this new diagnosis with more fatal outcomes than Kawasaki cases.
Highlights
In emergence a COVID patient with multisystem inflammatory syndrome in children (MIS-C), associated with SARS-CoV-2, has shown increasing number among pediatric
Even the same presentation of Kawasaki disease we have to keep in mind MIS-C, in order to reach a consensus on this new disease in the future
A 10 year old girl not known to have any medical illness came to emergency with a history of fever for the last five days and lower abdominal pain
Summary
On December 19th, 2020, reported first case of (SARS-CoV-2) COVID-19. There are reports of frequent gastrointestinal involvement [6] and, among other symptoms, an incidence increase of Kawasaki or Kawasaki-like syndrome, when associated with SARS-CoV-2 [7] [8]. On April 7, 2020, the first case report of Kawasaki like disease (KD) and COVID-19 a six-month-old child with was published in the US. Cases occurred shortly after exposure to COVID-19 suggesting a possible temporal correlation with SARS-CoV-2 infection, as some patients had positive polymerase chain reaction (PCR) or serology. This syndrome was called the “multisystem inflammatory syndrome in children (MIS-C)” [9] [10] [11]
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