Abstract
Tricked or trapped-Two decoy mechanisms in host-pathogen interactions.
Highlights
A similar example of a pathogen-derived Receptor decoy is extracellular Protein-6 (Ecp6), a Lysin Motif (LysM)-containing effector that is secreted by the fungal pathogen Cladosporium fulvum during infection of tomato plants
A similar Bodyguard decoy concept has been proposed for truncated versions of Transcription Activator-like Effectors (TALEs) that are secreted by the bacterial plant pathogen Xanthomonas [7]
PBS1 is a Sensing decoy that mimics the target of AvrPphB and confers recognition of this effector by activating its binding partner Resistance to Pseudomonas syringae-5 (RPS5), an Nod-like Receptor (NLR) that triggers immune signalling [14]
Summary
Ectromelia virus (causative of mouse pox) encodes the Type 1-interferon binding protein (T1-IFNbp), a Receptor decoy that is essential for its virulence [2]. A similar example of a pathogen-derived Receptor decoy is extracellular Protein-6 (Ecp6), a Lysin Motif (LysM)-containing effector that is secreted by the fungal pathogen Cladosporium fulvum during infection of tomato plants. A similar Bodyguard decoy concept has been proposed for truncated versions of Transcription Activator-like Effectors (TALEs) that are secreted by the bacterial plant pathogen Xanthomonas [7].
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