Abstract
BackgroundTrichofolliculoma of the eyelid and periorbital region remains is rare, and there is limited evidence regarding surgical management, clinical and histological margins, and recurrence rate.ObjectivesWe performed a systematic review of cases to date on diagnosis and management outcomes of eyelid trichofolliculoma.MethodsElectronic databases were searched for cases reported on trichofolliculoma of the eyelid. The authors extracted and collated data from these studies, and outcomes were summarized descriptively.ResultsOne hundred twenty citations were identified from database searching. The authors also report a case of eyelid trichofolliculoma. Fifteen studies reporting 19 cases of eyelid trichofolliculoma were finally included. Eighteen out of 19 (94.7%) cases were treated with surgical excision. Of 5 cases which were followed up over an average of 2 years, there was only 1 case of recurrence requiring wedge resection.ConclusionsRecurrence rate in patients with eyelid trichofolliculoma excised with satisfactory margins appears to be low, and no cases of malignant transformation have been reported.
Highlights
Trichofolliculoma is a rare benign skin hamartoma of the pilosebaceous follicle, often seen in younger patients with predilection for face and scalp, with some rare cases affecting the eyelid (Simpson et al 1989; Ozdal et al 2003; Taniguchi & Hamada. 1996)
There are a number of dermatological pathologies that can be found on the eyelid and be treated surgically (Hu et al 2017; Kohli & Bordeaux. 2019; Martínez-Palmer et al 2017), there is a rarity of such literature for eyelid trichofolliculoma
Given the scarcity of published cases on eyelid trichofolliculoma, there is limited understanding regarding the recurrence rates and ideal surgical margins required for treatment
Summary
Trichofolliculoma is a rare benign skin hamartoma of the pilosebaceous follicle, often seen in younger patients with predilection for face and scalp, with some rare cases affecting the eyelid (Simpson et al 1989; Ozdal et al 2003; Taniguchi & Hamada. 1996). Given the scarcity of published cases on eyelid trichofolliculoma, there is limited understanding regarding the recurrence rates and ideal surgical margins required for treatment. Trichofolliculoma of the eyelid and periorbital region remains is rare, and there is limited evidence regarding surgical management, clinical and histological margins, and recurrence rate. Objectives: We performed a systematic review of cases to date on diagnosis and management outcomes of eyelid trichofolliculoma. Methods: Electronic databases were searched for cases reported on trichofolliculoma of the eyelid. The authors report a case of eyelid trichofolliculoma. Fifteen studies reporting 19 cases of eyelid trichofolliculoma were included. Conclusions: Recurrence rate in patients with eyelid trichofolliculoma excised with satisfactory margins appears to be low, and no cases of malignant transformation have been reported
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