Abstract
A series of aza analogs of the bisabolyl arid α-terpinyl cations were testedas inhibitors of the sesquiterpene cyclase, trichodiene synthase. Both (R)- arid (S)-16 arid (R)- arid (S)-13 aswell as trimethylamine were only weak inhibitors when incubated alone. In the presence of inorganic pyrophosphate, itself a known competitive inhibitor of trichodiene synthase, all five amines showed strong cooperativecompetitive inhibition with an enhancement factor estimated to be 10-40
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