Abstract
Distinguishing treatment-related imaging changes (TRIC) from true regrowth of brain metastases after stereotactic radiosurgery (SRS) is clinically challenging. This problem is further compounded by non-standardized interpretations of pathological specimens obtained from these lesions. The aim of the present study was to evaluate overall survival based on a pathologic review of lesions resected following SRS. Four pathologic stages were proposed a priori and the association with survival was then measured.
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