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Abstract
The year 2016 marked the 20th anniversary of the death of Marcelle Grenson and the 50th anniversary of her first publication on yeast amino acid transport, the topic to which, as Professor at the Free University of Brussels (ULB), she devoted the major part of her scientific career. M. Grenson was the first scientist in Belgium to introduce and apply genetic analysis in yeast to dissect the molecular mechanisms that were underlying complex problems in biology. Today, M. Grenson is recognized for the pioneering character of her work on the diversity and regulation of amino acid transporters in yeast. The aim of this tribute is to review the major milestones of her forty years of scientific research that were conducted between 1950 and 1990.
Highlights
Marcelle Grenson was born on 25 June 1925 in Brussels (Schaerbeek)
In 1960, she submitted a project proposal (I found in her archives), wherein she proposed to develop in Euglena genetic methods that were similar to those that were developed for yeast
The difficulties encountered, led her quickly to give up her studies on Euglena, to focus entirely on yeast, and to become familiar with the genetic methods developed for the latter microorganism
Summary
Marcelle Grenson was born on 25 June 1925 in Brussels (Schaerbeek) As she was gifted and diligent in school, her father (an electrician) wanted her to undertake secondary studies to become a teacher in primary school. She was interested in the logic of the electrical circuits her father designed at home, and she told me one day that those circuits may have triggered her early interest in regulatory mechanisms After graduating, she earned enough as a teacher to help Andrée, her sister, through teacher training. Raymond Jeener, who was head of the Animal Physiology Laboratory of the ULB, which was located in the vicinity of the Rouge-Cloître, near the Sonian Forest of Brussels The subject of her master’s thesis was “Growth characteristics of a flagellate in an iron-free synthetic medium”. In 1950, she obtained her Master’s Degree in Zoological Science
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