Tribochemical Component of Oxidative Stress Development at Artificial Joints Implantation. Part 5. Pro-oxidative Properties and Interrelation of Titanium and Non-Metallic Orthopaedic Material Wear Particles with Antioxidants

Abstract

Radical-forming ability of artificial wear particles of BT6 titanium alloy and nonmetallic materials was studied using modelling reaction of cumene oxidation. It was stated that alloy particles initiate formation of radicals and consecutive repeated cumene oxidation by metallic particles took place with significantly higher rate of radicals’ formation. Particles of nonmetallic materials (polyethylene, corundum ceramics, carbon nanocomposite) are inert and do not possess radical-forming ability that ensures their advantage in prevention of possible development of adverse free radical reactions in surrounding implant tissues.