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Abstract
Abstract Triazine is a six-membered aromatic nitrogen heterocyclic moiety that was extensively investigated because of its biological properties and, in particular anticancer potentials. Kinases play a crucial role in cancer cell proliferation and metabolism. Triazine derivatives show anticancer activity by inhibiting the lipid kinases like phosphoinositide 3-kinases, mammalian target of rapamycin, receptor tyrosine kinases, like focal adhesion kinase, cyclin-dependent kinases, Rho-associated protein kinases, p21-activated kinases, carbonic anhydrases, enolase inhibitors, microtubules inhibitors, and histone deacetylases. The present chapter highlights the synthesis of triazine-based derivatives, their characterization, evaluation of anticancer properties, and their journey towards possible medicine for cancer.
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