Abstract
What is already known about this topic? Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide. With large amounts of financial support devoted for prevention and related interventions for birth defects, huge progress has been made as a 60% decrease in its prevalence was observed from 2009 to 2014. What is added by this report? The study presented a recent trend of adverse pregnancy outcomes (APOs) in Shanxi Province, a region with high prevalence of birth defects in China from 2007–2019. The prevalence of serious APOs including birth defects, stillbirths, and neonatal deaths remained at a relatively low level, yet macrosomia, low birth weight (LBW), preterm births, and spontaneous abortion comprised a majority of all APOs, with macrosomia showing an obvious upward trend from 2007 to 2012. What are the implications for public health practice? These findings provide new evidence for prevention and intervention strategies of APOs in northern China. Future research should focus on comprehensive interventions for multiple APOs, especially macrosomia, LBW, preterm births, and spontaneous abortion.
Highlights
China CDC WeeklyTrends of Adverse Pregnancy Outcomes in a High Prevalence Region of Birth Defects — Shanxi Province, China, 2007–2019
Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide and the highest prevalence of neural tube defects in the world [1]
Since over 30 years ago, large amounts of financial support have been devoted for the prevention of birth defects and related intervention, and huge progress has been made as a 60% decrease in its prevalence was observed from 2009 to 2014 [2]
Summary
Trends of Adverse Pregnancy Outcomes in a High Prevalence Region of Birth Defects — Shanxi Province, China, 2007–2019. Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide. The study presented a recent trend of adverse pregnancy outcomes (APOs) in Shanxi Province, a region with high prevalence of birth defects in China from 2007–2019. Our study aimed to investigate the trends of prevalence of APOs at birth and to provide evidence for new strategies for APO prevention and intervention in rural areas in northern China. APOs were defined as neonatal deaths, stillbirths, birth defects, low birth weight, macrosomia, preterm births and spontaneous abortion. The prevalence of APOs was calculated by using the total
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