Abstract
s 473 (RR 0.58; 95% CI 0.41; 0.83; P50.003). The number needed to treat to prevent one episode of postoperative AF is 20 patients. Significant heterogeneity was noted among the reported outcome, which was mainly driven by one trial. Upon examining trials that looked at the use of AF in patients undergoing CABG, statin was associated with 53% reduction in postoperative AF ((RR 0.47; 95% CI 0.34; 0.63; P,0.001). The number needed to treat to prevent one episode of postoperative AF is three patients. No evidence of heterogeneity was observed among the reported outcome. Conclusions: In patient undergoing cardiac surgery, patient will likely benefit from preoperative statin therapy to prevention POAF.
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