Abstract
Atrial septal defect (ASD) is a non-physiologic communication between the two atria, allowing the shunt between systemic and pulmonary circulation. Data about ASD prevalence among congenital heart disease patients (CHD) in Vietnam are still scarce. We aim to assess the trends in the prevalence of ASD patients and associated factors among CHD patients. This was a cross-sectional study, with data collected from medical records from 1220 CHD patients in Da Nang hospital from 1 January 2010 to 31 December 2015. Descriptive statistics were used to estimate the prevalence of ASD among CHD patients. Comparative statistical methods were used to compare groups and logistic regression to access associated factors with ASD. The overall prevalence of ASD among CHD patients was 18.5% between 2010 and 2015. The prevalence varied between periods, ranging between 15% and 31.9% during the period. The prevalence of ASD women among CHD (25.9%) was significantly higher than for men (16.0%). The prevalence of ASD increased gradually when the age group increased. The factors associated with increased ASD prevalence were being a female and being in an older age group. The findings suggest that targeted policy should provide more-specific health-care services of ASD for women and older patients.
Highlights
Atrial septal defect (ASD) is a non-physiologic communication between the two atria of the heart, which allows shunting between the systemic and the pulmonary circulations
The data about the status of ASD as the hospital-based level are still scarce, so the aim of this study was to assess the prevalence of ASD among congenital heart disease (CHD) patients and its associated factors among CHD patients who used surgical and transcatheter closure intervention in Vietnam
The prevalence of ASD in our study varied between 15.0% and 31.9% in six years, so these results were in line with the prevalence found in other Southeast Asia countries [19,20,21]; they were slightly higher than the worldwide prevalence of ASD among CHD patients, which was estimated at 15.4% [18]
Summary
Atrial septal defect (ASD) is a non-physiologic communication between the two atria of the heart, which allows shunting between the systemic and the pulmonary circulations. The estimated incidence worldwide is 56 per 100,000 live births and the prevalence of 1.6 per 1000 live births [6,7]. With improved detection of clinically silent defects by echocardiography, the estimated incidence is expected to be of 100 per 100,000 live births [6]. ASD is the most common form of CHD that goes under detected during childhood. In adults, it accounts for 7% to 10% of all CHD and between 20% and 40% of all newly diagnosed CHD [1,8]
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