Abstract
IntroductionThyroid cancer (TC) incidence has been increasing in recent years. The aim of this study was to investigate our institution-based estimates of operative volumes for TC over the last three decades.Materials and methodsThis was a retrospective cohort study of patients undergoing thyroid surgery at our institution. Patient characteristics were reviewed in three subgroups: Group I (treated in 1981–1986), Group II (treated in 1987–2002), and Group III (treated in 2003–2012).ResultsTC was diagnosed in 1578/17,526 (9.0 %) thyroid operations. Incidence of TC increased from 3.7 % in Group I to 10.4 % in Group III (p < 0.001). Incidence of papillary TC increased form 40.6 % in Group I to 81.3 % in Group III (p < 0.001). In the latter group, 23.5 % of all papillary TCs were diagnosed in patients with Hashimoto’s disease. Meanwhile, incidence of anaplastic TC decreased from 16.2 % in Group I to 2.1 % in Group III patients (p < 0.001). pT1 tumors were diagnosed in 8.1 % Group I and 54.8 % Group III (p < 0.001), whereas pT4 tumors were identified in 40.5 % Group I, 2.4 % Group II, and 0.84 % Group III subjects (p < 0.001). pT3 tumors were found in 51.6 % Group I, whereas multifocal papillary TCs were found in 15.7 % Group III patients, the latter with a higher prevalence of pN1 stage (p < 0.001).ConclusionsThe following trends in surgical volume for TC were identified throughout the study period: a fivefold increase of thyroid operations for TC, a threefold increase in incidence of papillary TC, and an eightfold decrease in incidence of anaplastic TC. It is of interest that a significant increase in incidence of multifocal papillary TC in young female patients with Hashimoto’s disease was found over time.
Highlights
Thyroid cancer (TC) incidence has been increasing in recent years
Incidence of anaplastic TC decreased from 16.2 % in Group I to 2.1 % in Group III patients (p \ 0.001). pT1 tumors were diagnosed in 8.1 % Group I and 54.8 % Group III (p \ 0.001), whereas pT4 tumors were identified in 40.5 % Group I, 2.4 % Group II, and 0.84 % Group III subjects (p \ 0.001). pT3 tumors were found in 51.6 % Group I, whereas multifocal papillary TCs were found in 15.7 % Group III patients, the latter with a higher prevalence of pN1 stage (p \ 0.001)
The following trends in surgical volume for TC were identified throughout the study period: a fivefold increase of thyroid operations for TC, a threefold increase in incidence of papillary TC, and an eightfold decrease in incidence of anaplastic TC
Summary
Thyroid cancer (TC) incidence has been increasing in recent years. The aim of this study was to investigate our institution-based estimates of operative volumes for TC over the last three decades. Incidence of papillary TC increased form 40.6 % in Group I to 81.3 % in Group III (p \ 0.001) In the latter group, 23.5 % of all papillary TCs were diagnosed in patients with Hashimoto’s disease. Poland represents rather low incidence rates, according to the National Cancer Register (NCR), the total number of malignant thyroid cases in the Polish population has increased 4 times in females and 3 times in males within the past decades. In spite of improvement of the afore-mentioned diagnostic methods, a high number of cases of thyroid cancer (more than 30 %) are diagnosed only in postoperative histopathology, what necessitates a reoperation in the patient and is associated with increased costs of treatment [4,5,6,7,8]
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