Abstract

SummaryBackgroundTo contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050.MethodsWe did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. Only studies with samples representative of the population and with clearly defined visual acuity testing protocols were included. We fitted hierarchical models to estimate 2020 prevalence (with 95% uncertainty intervals [UIs]) of mild vision impairment (presenting visual acuity ≥6/18 and <6/12), moderate and severe vision impairment (<6/18 to 3/60), and blindness (<3/60 or less than 10° visual field around central fixation); and vision impairment from uncorrected presbyopia (presenting near vision <N6 or <N8 at 40 cm where best-corrected distance visual acuity is ≥6/12). We forecast estimates of vision loss up to 2050.FindingsIn 2020, an estimated 43·3 million (95% UI 37·6–48·4) people were blind, of whom 23·9 million (55%; 20·8–26·8) were estimated to be female. We estimated 295 million (267–325) people to have moderate and severe vision impairment, of whom 163 million (55%; 147–179) were female; 258 million (233–285) to have mild vision impairment, of whom 142 million (55%; 128–157) were female; and 510 million (371–667) to have visual impairment from uncorrected presbyopia, of whom 280 million (55%; 205–365) were female. Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). In this period, the number of people who were blind increased by 50·6% (47·8 to 53·4) and the number with moderate and severe vision impairment increased by 91·7% (87·6 to 95·8). By 2050, we predict 61·0 million (52·9 to 69·3) people will be blind, 474 million (428 to 518) will have moderate and severe vision impairment, 360 million (322 to 400) will have mild vision impairment, and 866 million (629 to 1150) will have uncorrected presbyopia.InterpretationAge-adjusted prevalence of blindness has reduced over the past three decades, yet due to population growth, progress is not keeping pace with needs. We face enormous challenges in avoiding vision impairment as the global population grows and ages.FundingBrien Holden Vision Institute, Fondation Thea, Fred Hollows Foundation, Bill & Melinda Gates Foundation, Lions Clubs International Foundation, Sightsavers International, and University of Heidelberg.

Highlights

  • VISION 2020: The Right to Sight, a joint global initiative for the elimination of avoidable blindness between WHO and the International Agency for the Prevention of Blindness, has galvanised efforts to systematically eliminate avoidable blindness.[1,2] the adop­ tion of the resolution Towards universal eye health: a global action plan 2014–2019 by the World Health Assembly renewed ideals and strategies for Member States to amplify initiatives to prevent vision impairment and promote low vision rehabilitation in their populations.[3]The Vision Loss Expert Group (VLEG) populates and curates the Global Vision Database, a continuously updated, comprehensive, online database storing world­ wide ophthalmic epidemiological information

  • Eligible studies from this review were combined with data from Rapid Assessment of Avoidable Blindness (RAAB) studies by VLEG and data from the US National Health and Nutrition Examination survey and the WHO Study on Global Ageing and Adult Health were contributed by the Global Burden of Disease Study (GBD) team

  • We included studies that met the following criteria: visual acuity data had to be measured using a test chart that could be mapped to the Snellen scale, and the sample had to be representative of the population

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Summary

Introduction

VISION 2020: The Right to Sight, a joint global initiative for the elimination of avoidable blindness between WHO and the International Agency for the Prevention of Blindness, has galvanised efforts to systematically eliminate avoidable blindness.[1,2] the adop­ tion of the resolution Towards universal eye health: a global action plan 2014–2019 by the World Health Assembly renewed ideals and strategies for Member States to amplify initiatives to prevent vision impairment and promote low vision rehabilitation in their populations.[3]The Vision Loss Expert Group (VLEG) populates and curates the Global Vision Database, a continuously updated, comprehensive, online database storing world­ wide ophthalmic epidemiological information. We estimated that in 2015, 36·0 million people were blind, 217 million had moderate and severe vision impairment, 188 million had mild vision impairment, and 667 million additional people (aged ≥50 years) had vision impairment from uncorrected presbyopia.[4] These 2015 estimates were used for the World report on vision, published by WHO in 2019.5 We. For the Global Vision Database see https://www. Evidence before this study The Vision Loss Expert Group (VLEG) previously published global, regional, and country-level estimates of mild or more severe distance vision impairment from 1990 to 2015. They found an overall decrease in age-standardised prevalence of distance vision but an increase in total people with vision loss. An important contribution to the WHO initiative, VISION 2020: The Right to Sight, these studies are unique in providing granular estimates that are sex, age, and country specific, and assess temporal trends

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