Trends in mortality from tumors of the central nervous system in adults, Rio de Janeiro, 1980-2010

Abstract

Background: Tumors of the Central Nervous System (CNS) are relatively rare in adults, but they present a high mortality rate: only half of the cases survive one year after diagnosis. Aims: To describe the mortality pattern from CNS tumors in adults in the city of Rio de Janeiro, Brazil, from 1980 to 2010. Methods: We conducted a descriptive study of deaths through the Consolidated Information System on Mortality. We calculated crude and adjusted mortality rates, as well as gender, age and tumor-specific mortality rates. For trend analysis, regression models were performed and the EAPC (Estimated Annual Percentage Change) was calculated. Results: In 1980, the mortality ratewas4.97/100,000 person-years, while in 2010the ratereached7.91/100,000 person-years. During the study period, most deaths were observed in white men, and occurred due to malignant tumors located in the encephalon. The standardized mortality rate for CNS tumors in adults over age 19 years increased 1% annually throughout the period. This increase was greater in women: 1.7% per year. Conclusions: The patterns of mortality from CNS tumors in the municipality of Rio de Janeiro are in accordance with global trends. Therefore, it is recommended to develop analytical studies to identify risk factors associated with these tumors, which may include genetic and environmental factors.